Search results for "Radical vaginal trachelectomy"

showing 5 items of 5 documents

Validity of Laparoscopic Staging to Avoid Adjuvant Chemoradiation following Radical Surgery in Patients with Early Cervical Cancer

2012

<b><i>Purpose:</i></b> To determine the rate of unavoidable adjuvant chemoradiation (RCTX) due to histologic results after radical surgery in patients with early cervical cancer. <b><i>Patients and Methods:</i></b> Between May 2004 and July 2011, 448 consecutive patients diagnosed with invasive cervical cancer stage IA1 L1 to IIA underwent laparoscopic staging at the Department of Gynecology and Gynecologic Oncology at Charité Berlin. Only in patients without lymph node metastases (n = 394) on frozen section, radical operation was continued either by laparoscopic radical hysterectomy (n = 228) or by radical vaginal trachelectomy (n = 166). The…

AdultCancer Researchmedicine.medical_specialtyAdolescentmedicine.medical_treatmentUterine Cervical NeoplasmsRadical vaginal trachelectomyAdjuvant chemoradiationHysterectomyYoung AdultRisk FactorsEarly cervical cancermedicineHumansRadical hysterectomyProspective StudiesRadical HysterectomyRadical surgeryLaparoscopyProspective cohort studyAgedNeoplasm StagingAged 80 and overCervical cancerHysterectomymedicine.diagnostic_testbusiness.industryGeneral surgeryChemoradiotherapy AdjuvantGeneral MedicineMiddle Agedmedicine.diseaseSettore MED/40 - Ginecologia E OstetriciaSurgeryClinical trialOncologyLymphatic MetastasisAdjuvant chemoradiation; Early cervical cancer; Radical hysterectomyVaginaLymph Node ExcisionFemaleLaparoscopyRisk factorbusinessChemoradiotherapy
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Prevalence of lymph nodes in the parametrium of radical vaginal trachelectomy (RVT) specimen

2011

Objective: In order to evaluate radicality in fertility preserving surgery in women with early invasive cervical cancer we analyzed the parametrium of specimens of patients treated by radical vaginal trachelectomy for the presence of lymph nodes. We tried to identify morphologic factors associated with the presence of parametrial lymph nodes. Methods: We analyzed surgical specimens of 112 patients who underwent radical trachelectomy between June 2004 and April 2009 at the Department of Gynecologic Oncology at Charité Campus Benjamin Franklin and Campus Mitte. All parametrial tissue was step sectioned and a total of 1878H&E stained histological sections were analyzed. Results: In 8 patients …

Adultmedicine.medical_specialtyUterine Cervical NeoplasmBroad LigamentEarly stage cervical cancerUterine Cervical NeoplasmsHistopathologyRadical vaginal trachelectomyTrachelectomyGynecologic oncologyMetastasisGynecologic Surgical ProceduresGynecologic Surgical ProcedureParametriummedicinePrevalenceHumansCervical cancerbusiness.industryParametrialLymph NodeObstetrics and GynecologyLymphatic Metastasimedicine.diseaseImmunohistochemistrySurgeryEarly stage cervical cancer; Radical vaginal trachelectomy; Parametrial resectionmedicine.anatomical_structureParametrial lymph nodeOncologyLymphatic MetastasisParametrial resectionHistopathologyFemaleLymph NodesLymphbusinessHuman
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Radical vaginal trachelectomy (RVT) combined with laparoscopic lymphadenectomy: Prospective study of 225 patients with early-stage cervical cancer

2011

Objective: The aim of the study was to prove the surgical and oncological safety of radical vaginal trachelectomy (RVT) and laparoscopic lymphadenectomy for patients with early-stage cervical cancer who are seeking parenthood. Methods: A database of 225 patients with early-stage cervical cancer and intention to treat by RVT after laparoscopic lymphadenectomy was prospectively maintained. A total of 212 patients were treated according to the protocol. The procedure was preformed in a standardized manner, and life table analysis was applied. Results: In the cohort of patients treated according to protocol, 8 recurrences occurred and 4 patients died from recurrence. The median follow-up time w…

Adultmedicine.medical_specialtyUterine Cervical NeoplasmUrologyUterine Cervical NeoplasmsRadical vaginal trachelectomyAdenocarcinomaYoung AdultGynecologic Surgical ProceduresGynecologic Surgical ProcedureVaginal TrachelectomyEarly-stage cervical cancer; Fertility-preserving surgery; Radical vaginal trachelectomyMedicineHumansProspective StudiesStage (cooking)Prospective cohort studyLaparoscopic lymphadenectomyCervical cancerLaparoscopic lymphadenectomyIntention-to-treat analysisbusiness.industryMedicine (all)Fertility-preserving surgeryObstetrics and GynecologyPerioperativeMiddle Agedmedicine.diseaseSettore MED/40 - Ginecologia E OstetriciaSurgeryProspective StudieOncologyEarly-stage cervical cancerCohortVaginaCarcinoma Squamous CellLymph Node ExcisionFemaleLaparoscopybusinessHuman
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Fertility outcome after radical vaginal trachelectomy: a prospective study of 212 patients.

2011

ObjectiveFor treatment in patients with early-stage cervical cancer, radical vaginal trachelectomy (RVT) as a fertility-preserving surgery can be put on a par with radical hysterectomy as to oncologic safety. Our aim was to investigate the fertility concerns and outcome.MethodsProspective collection of fertility data of patients treated with RVT. The data were collected on personal communication, by telephone, or e-mail correspondence. Descriptive statistical analysis was performed.ResultsBetween March 2005 and April 2010, 212 patients were followed up after RVT. Only 76 patients (35.9%) were seeking parenthood currently. Sixty pregnancies occurred in 50 women. Five patients (8.3%) had firs…

Fertility-preserving treatmentAdultmedicine.medical_specialtyUterine Cervical Neoplasmmedia_common.quotation_subjectRadical vaginal trachelectomyUterine Cervical NeoplasmsFertilityMiscarriageYoung AdultGynecologic Surgical ProceduresObstetrics and gynaecologyGynecologic Surgical ProcedurePregnancyEarly-stage cervical cancer; Fertility-preserving treatment; Pregnancy after cervical cancermedicineHumansFertility preservationProspective StudiesProspective cohort studymedia_commonNeoplasm StagingGynecologyCervical cancerPregnancyEctopic pregnancyObstetricsbusiness.industryPregnancy after cervical cancerMedicine (all)Pregnancy OutcomeObstetrics and GynecologyFertility PreservationMiddle Agedmedicine.diseaseSettore MED/40 - Ginecologia E OstetriciaProspective StudieTreatment OutcomeOncologyEarly-stage cervical cancerFemalebusinessHumanInternational journal of gynecological cancer : official journal of the International Gynecological Cancer Society
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Laparoscopic lymph node dissection should be performed before fertility preserving treatment of patients with cervical cancer

2012

Objective: The aim of this study is to assess our results of treatment of women with stage I cervical cancer > 2 cm in diameter seeking fertility preservation. Treatment consisted of Laparoscopic Pelvic and Paraaortic Lymphadenectomy (LPPLND), and when no nodal metastasis was detected, neoadjuvant chemotherapy (NACT) followed by radical vaginal trachelectomy (RVT). Patients with positive lymph nodes underwent primary chemoradiation. Methods: A cohort of women younger than 40 years of age with stage I disease > 2 cm who underwent LPPLND and either NACT and RVT or chemoradiation. Oncological outcome was evaluated prospectively. Results: Eighteen women were eligible for this study. Twelve (67%…

Uterine Cervical NeoplasmRVTmedicine.medical_treatmentBrachytherapyUterine Cervical NeoplasmsCervix UteriMetastasisParaaortic lymph nodesAntineoplastic Combined Chemotherapy ProtocolsMedicineProspective StudiesFertility preservationProspective cohort studyLymph nodeNeoadjuvant therapyCervical cancerFertility PreservationObstetrics and GynecologyChemoradiotherapyNeoadjuvant Therapymedicine.anatomical_structureOncologyChemotherapy AdjuvantLymphatic MetastasisCarcinoma Squamous CellFemaleRadiologyHumanAdultmedicine.medical_specialtyPaclitaxelPelviRadical vaginal trachelectomyCervical carcinoma; Radical vaginal trachelectomy; Neoadjuvant chemotherapyAdenocarcinomaNeoadjuvant chemotherapyPelvisFollow-Up StudieHumansIfosfamideCervical carcinomaNeoplasm StagingAntineoplastic Combined Chemotherapy Protocolbusiness.industryGeneral surgeryLymphatic Metastasimedicine.diseaseProspective StudieLymph Node ExcisionLaparoscopyCisplatinNeoplasm Recurrence LocalbusinessChemoradiotherapyFollow-Up Studies
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